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目的了解HBV感染者发生肾损害的情况,为临床治疗及提高HBV感染者生活质量提供参考。方法收集2008年1月~2011年3月期间在本院就诊病人中检出的955例HBV感染者的临床资料,对其肾损伤情况进行统计分析。结果出现肝损害者发生肾损害的比例高于未出现肝损害者(P<0.01);男性HBV感染者肾损害的发生率高于女性感染者(P<0.01),发生率分别为18.1%和7.1%;HBV感染者肾损害的发生率在不同年龄的人群中也具有差异(P<0.01),在≥51岁的感染者中较为常见。结论 HBV感染者肾损害的发生率较高,临床应密切监视HBV感染者特别是出现肝损害、≥51岁及男性的肾功能情况。
Objective To understand the situation of kidney damage in patients with HBV infection and provide references for clinical treatment and improving the quality of life of HBV infected persons. Methods The clinical data of 955 cases of HBV infection detected in our hospital from January 2008 to March 2011 were collected and their renal damage were statistically analyzed. Results The incidence of renal damage in patients with liver damage was higher than that in patients without liver damage (P <0.01). The incidence of renal damage in male patients with HBV infection was higher than that in women (P <0.01), and the incidence rates were 18.1% 7.1%. The incidence of renal damage in HBV-infected persons also had differences among different age groups (P <0.01), and was more common in those who were 51 years or older. Conclusion The incidence of renal damage in HBV-infected patients is high. Clinically, HBV infection should be closely monitored, especially in patients with liver damage, ≥51 years old and male renal function.