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本文探索高强度超声在击碎粥样斑块和血栓时能否不损伤正常血管壁;确定达到此效应的能量强度;研究碎片的大小和组织损伤。方法从24例死后12小时内的尸体中获得的胸或腹主动脉标本,切成4×6cm片状,纵向打开,内膜向上平放,浸于生理盐水中。根据肉眼观察及触摸判断病理类型,并用墨汁标出。然后将标本固定于中性缓冲液中,用oal-EXII脱钙,石腊包埋,切成5μm厚的薄片。共591份标本,其中正常279份,钙化93份,纤维斑块119份。使高强度的 20kH_z超声探头垂直于组织,采用5种不同能量级别,
This article explores high-intensity ultrasound in crushing atherosclerotic plaques and thrombosis can damage the normal blood vessel wall; determine the energy intensity to achieve this effect; study the size of debris and tissue damage. Methods Thoracic or abdominal aorta specimens obtained from 24 dead bodies within 12 hours after the death were cut into 4 × 6 cm pieces and opened longitudinally. The intima was placed flat and immersed in saline. According to the naked eye observation and touch to determine the pathological type, and marked with ink. The specimens were then fixed in neutral buffer, decalcified with oal-EXII, embedded in paraffin and cut into 5 μm thick slices. A total of 591 specimens, of which 279 were normal, 93 were calcified, fibrous plaque 119. The high-intensity 20kH_z ultrasound probe perpendicular to the tissue, using five different energy levels,