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近年发现细胞免疫和体液免疫对肝病的发病具重要作用,机体的免疫状态、免疫反应的强度影响着疾病的临床表现、过程与结局。作者等研究了22例迁延型病毒性肝炎、30例慢性病毒性肝炎(其中7例为慢性活动性肝炎)、15例肝硬变、19例无症状HBsAg携带者的T和B淋巴细胞数量和血清IgM、IgA、IgG的水平。全部病例的诊断均经肝穿刺组织学检查所证实。患者的年龄为19～55岁。按Mendes等(1974)法测定T和B淋巴细胞,按Manchini氏(1965)的放射免疫扩散法测血清IgA、IgM、IgG。正常值指标系来自供血者,其T淋巴细胞为
In recent years, found that cellular immunity and humoral immunity play an important role in the pathogenesis of liver disease, the immune status of the body, the intensity of the immune response affects the clinical manifestations, processes and outcomes of the disease. The authors studied 22 cases of persistent viral hepatitis, 30 cases of chronic viral hepatitis (7 cases of chronic active hepatitis), 15 cases of cirrhosis, 19 cases of asymptomatic HBsAg carriers T and B lymphocytes and serum IgM, IgA, IgG levels. All cases were diagnosed by liver biopsy confirmed by histology. The patient’s age is 19 to 55 years old. T and B lymphocytes were assayed by the method of Mendes et al. (1974), and serum IgA, IgM and IgG were measured by radioimmunoassay of Manchini’s (1965). Normal index system from the donor, the T lymphocytes