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目的:探讨期待治疗对不同孕周早发型重度子痫前期对母儿结局的影响。方法:对178例不同孕周的早发型子痫前期重度进行回顾性分析。根据发病孕周分成A组(孕周<28周)31例、B组(28周≤孕周<32周)61例、C组(32周≤孕周<34周)86例。结果:B组期待治疗的时间显著长于其他两组(P<0.05);B组、C组分娩方式以剖宫产为主;3组间患者并发症发生率无统计学差异(P>0.05);3组间新生儿窒息发生率及围生儿死亡率有统计学差异(P<0.05),随着孕周延长而下降。结论:早发型重度子痫前期期待治疗入选孕周越小,母儿并发症率、新生儿患病率及死亡率越高。
Objective: To investigate the effect of expectant treatment on the outcomes of early gestational age-severe pre-eclampsia on maternal and infant outcomes in different gestation weeks. Methods: A retrospective analysis was performed on 178 cases of pre-eclampsia with different gestational age. According to the gestational age, there were 31 cases in group A (gestational age <28 weeks), group B (28 weeks ≤ gestational weeks <32 weeks), and group C (32 weeks ≤ gestational weeks <34 weeks) in 86 cases. Results: The duration of expectant treatment in group B was significantly longer than that in the other two groups (P <0.05). Cesarean delivery was the main mode of delivery in groups B and C. There was no significant difference in the complication rates between the three groups (P> 0.05) There was a significant difference in the incidence of neonatal asphyxia and perinatal mortality between the three groups (P <0.05), but decreased with the prolonged gestational age. Conclusions: The shorter gestational weeks for early onset severe preeclampsia, the higher rates of maternal and child complications, neonatal morbidity and mortality.