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作者在香港对抗结核化疗前痰菌药敏试验的价值进行了临床对照观察。药敏试验包括异菸肼,PAS和链霉素3种药物,25％的病人先前曾接受过不到4个月的化疗。本文报告3年观察的结果。病人随机分配以下3个治疗组: A组:先用链霉素、异菸肼、PAS治疗,继以异菸肼加PAS,不考虑治前药敏情况。 B组:按以上标准化疗,如药敏指示有抗药菌则换药。药敏试验用标准的间接法。 C组:先作玻片培养敏感试验,并根据此种药敏结果选择化疗。
The authors conducted a controlled clinical trial of the value of sputum bacterial susceptibility testing in Hong Kong before TB chemotherapy. Susceptibility testing includes isoniazid, PAS and streptomycin, and 25% of patients had previously undergone chemotherapy for less than 4 months. This article reports the results of 3 years of observation. Patients were randomly assigned to the following three treatment groups: Group A: first with streptomycin, isoniazid, PAS treatment, followed by isoniazid plus PAS, regardless of pre-treatment drug sensitivity. Group B: according to the above standard chemotherapy, such as antimicrobial susceptibility instructions are dressing change. Susceptibility testing using standard indirect method. Group C: first for slide culture sensitivity test, and based on the results of this drug sensitivity chemotherapy.