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目的探讨脂蛋白(a)与胆红素联合检测在冠状动脉粥样硬化性心脏病患者(CHD)中诊断的价值。方法选取2014年9月至2015年9月辽宁省朝阳市中心医院收治的60例CHD患者作为观察组,另外选取同期于我院进行体检的健康人员60例作为对照组,检测两组受试者总胆红素、直接胆红素及脂蛋白(a)水平。结果观察组患者的总胆红素、直接胆红素水平均明显低于对照组,脂蛋白(a)明显高于对照组,差异有统计学意义(P<0.05)。结论脂蛋白(a)升高及胆红素值降低与CHD发生、发展密切相关,临床诊断CHD时,联合检测脂蛋白(a)与胆红素检具有一定临床价值。
Objective To investigate the value of the combination of lipoprotein (a) and bilirubin in the diagnosis of coronary atherosclerotic heart disease (CHD). Methods Sixty CHD patients admitted from Chaoyang Central Hospital in Liaoning Province from September 2014 to September 2015 were selected as the observation group. Sixty healthy subjects who were in our hospital during the same period were selected as the control group. Two groups of subjects Total bilirubin, direct bilirubin and lipoprotein (a) levels. Results The levels of total bilirubin and direct bilirubin in the observation group were significantly lower than those in the control group. The level of lipoprotein (a) in the observation group was significantly higher than that in the control group (P <0.05). Conclusions The increase of lipoprotein (a) and the decrease of bilirubin value are closely related to the occurrence and development of CHD. Combined detection of lipoprotein (a) and bilirubin in clinical diagnosis of CHD has some clinical value.