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多巴胺转运体(dopam ine transporter,DAT)成像属于脑功能成像,其最初的开发是基于帕金森病(Parkinson d isease,PD)的诊断。然而随着核医学的不断发展,DAT成像正显示出越来越显著的应用价值。1 DAT的结构及功能DAT是位于中枢多巴胺(DA)能神经元突触前膜上的膜蛋白,由约620个氨
Dopamine transporter (DAT) imaging belongs to brain imaging and its initial development is based on the diagnosis of Parkinson’s disease (PD). However, with the continuous development of nuclear medicine, DAT imaging is showing more and more significant application value. Structure and function of DAT DAT is a membrane protein located on the presynaptic membrane of central dopaminergic neurons and consists of about 620 ammonia