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应用基因工程技术取代单个氨基酸改变抗体精细的特异性［英／ＫｎｓｓｉｅＰＨ．．．／／ＪＩｍｍｕｎｏｌ１９９４；１５２（１）：１４６］具有Ａｒｓ（偶氮苯砷酸盐）特异性抗体重链高变区的个别氨基酸被替代后，针对原半抗原Ａｒｓ的特异性消失，而改变为针对结构相似...
The use of genetic engineering to replace single amino acids alters the fine specificity of antibodies [Eng / KnssiePH. . . // JImmunol 1994; 152 (1): 146] After the replacement of individual amino acids with the Ars (azobenzene arsenate) specific antibody heavy chain hypervariable region, the specificity for the hapten Ars disappeared and was changed to Similar structure ...