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横纹肌溶解症(rhabdomyolysis,RM)是由于挤压、运动、高热、药物、炎症等原因所致横纹肌破坏和崩解,导致肌酸激酶、肌红蛋白等肌细胞内成分进入细胞外液及血循环,引起内环境紊乱、急性肾损伤(acute kidney injury,AKI)等组织器官损害的临床综合征,是引起急性肾损伤的主要原因之
Rhabdomyolysis (RM) is the destruction and disintegration of striated muscle due to crush, exercise, fever, drugs, inflammation and other factors, leading to intracellular fluid components such as creatine kinase and myoglobin entering the extracellular fluid and blood circulation, Caused by the internal environment disorders, acute kidney injury (AKI) and other tissue and organ damage clinical syndrome, is the main cause of acute kidney injury