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目的 观察 β -七叶皂甙钠与甘露醇合用治疗急性脑水肿的临床效果。 方法 将 90例急性脑水肿患者随机分为治疗组和对照组 ,每组 45例。治疗组用 β -七叶皂甙钠 10~ 2 0mg加入 5 %葡萄糖液 2 5 0~ 5 0 0ml静滴及 2 0 %甘露醇 12 5~ 2 5 0ml/次 ,3~ 4次 /d ,另外给予常规治疗 ,连用 2周 ;对照组用甘露醇与常规治疗。结果 治疗组的疗效明显优与对照组的疗效 (P <0 0 5 )。结论 β -七叶皂甙钠与甘露醇合用治疗急性脑水肿疗效确切、安全可靠、简捷方便 ,值得临床推广。
Objective To observe the clinical effect of combined use of β - aescinate and mannitol in the treatment of acute cerebral edema. Methods Ninety patients with acute cerebral edema were randomly divided into treatment group and control group, 45 cases in each group. Treatment group with β - aescin 10 ~ 20mg added 5% glucose solution 250 ~ 500 ml intravenous infusion and 20% mannitol 125 ~ 250ml / time, 3 ~ 4 times / d, in addition to Given conventional treatment, once every 2 weeks; control group with mannitol and conventional treatment. Results The curative effect of the treatment group was better than that of the control group (P <0.05). Conclusion The combination of β - aescinate and mannitol in treating acute cerebral edema is effective, safe and reliable, simple and convenient, and worthy of clinical promotion.