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目的探讨T2DM患者血清中性粒细胞/淋巴细胞比值(NLR)与DR的相关性。方法将128例T2DM患者分为增殖型DR(PDR)者22例、非增殖型DR(NPDR)者44例和单纯T2DM者62例。检测各组FPG、HbA1c、TC、TG和NLR等指标水平。结果Spearman相关性分析显示,DR与T2DM病程、SBP、DBP、FPG、HbA1c、TC、TG、LDL-C、NLR、CKD呈正相关(r=0.524、0.277、0.279、0.194、0.271、0.208、0.223、0.358、0.621、0.362,P<0.05或P<0.01)。Logistic多元回归分析结果显示,T2DM病程、NLR和糖尿病慢性肾脏疾病(CKD)是DR的独立影响因素。结论 NLR与DR存在相关性。
Objective To investigate the relationship between serum neutrophil / lymphocyte ratio (NLR) and DR in T2DM patients. Methods 128 patients with T2DM were divided into proliferative DR (PDR) in 22 cases, non-proliferative DR (NPDR) in 44 cases and simple T2DM in 62 cases. The levels of FPG, HbA1c, TC, TG and NLR in each group were detected. Results Spearman correlation analysis showed that there was a positive correlation between DR and duration of T2DM, SBP, DBP, FPG, HbA1c, TC, TG, LDL-C, NLR and CKD (r = 0.524,0.277,0.279,0.194,0.271,0.208,0.223, 0.352, 0.621, 0.362, P <0.05 or P <0.01). Logistic multiple regression analysis showed that T2DM duration, NLR and diabetic chronic kidney disease (CKD) were independent risk factors for DR. Conclusion There is a correlation between NLR and DR.