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目的探讨磁共振动态增强(DCE-MRI)和扩散加权成像(DWI)对鼻咽癌不同临床分期的诊断价值。方法初诊鼻咽癌患者42例,均行DCE-MRI和DWI检查。K~(trans)、ADC对不同临床分期及T分期诊断采用ROC曲线分析。结果 K~(trans)值、ADC值与鼻咽癌临床分期及T分期分别呈正、负相关。K~(trans)与ADC对鼻咽癌早期及晚期诊断的敏感性、特异性、诊断效能分别为80%、88.9%、91.1%;53.3%、88.9%、68.1%。K~(trans)与ADC对鼻咽癌T1、T2和T3、T4期诊断的敏感性、特异性、诊断效能分别为83.3%、77.8%、83.4%;70.8%、61.1%、67.4%。结论 K~(trans)和ADC可以很好的对鼻咽癌临床分期进行诊断,且K~(trans)对鼻咽癌的早期诊断效果要好于ADC的诊断效果。
Objective To investigate the diagnostic value of dynamic contrast-enhanced magnetic resonance (DCE-MRI) and diffusion-weighted imaging (DWI) in different clinical stages of nasopharyngeal carcinoma. Methods Forty-two nasopharyngeal carcinoma patients were examined with DCE-MRI and DWI. K trans, ADC analysis of different clinical stages and T staging using ROC curve analysis. Results The values of K ~ (trans) and ADC were positively and negatively correlated with the clinical stage and T stage of nasopharyngeal carcinoma respectively. The sensitivity, specificity and diagnostic efficacy of K ~ (trans) and ADC for early and late diagnosis of nasopharyngeal carcinoma were 80%, 88.9%, 91.1%, 53.3%, 88.9% and 68.1%, respectively. The sensitivity, specificity and diagnostic efficacy of K ~ (trans) and ADC for the diagnosis of nasopharyngeal carcinoma at T1, T2, T3, T4 were 83.3%, 77.8%, 83.4%, 70.8%, 61.1%, 67.4%, respectively. Conclusions K trans and ADC can be used to diagnose the clinical stage of nasopharyngeal carcinoma, and the early transcranial diagnosis of nasopharyngeal carcinoma is better than that of ADC.