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本文检测了２５例慢性肾衰病人，１３例特发性远端肾小管性酸中毒病人及正常对照组２３人的尿可滴定酸度（ＴＡ）、铵离子（ＮＨ＋）排泄量。结果显示慢性肾衰和肾小管性酸中毒患者尿ＴＡ、ＮＨ＋明显低于正常对照组（Ｐ＜０．０１），但前者ＴＡ降低的程度不比后者显著，而ＮＨ＋二组病人间无明显差异．经相关性比较还显示，慢性肾衰病人尿ＮＨ＋与血Ｃｒ之间呈显著负相关．作者讨论了慢性肾衰时肾小管酸化功能障碍的特点及其原因．
In this study, 25 patients with chronic renal failure, 13 patients with idiopathic distal renal tubular acidosis and normal control group of 23 patients with urinary titratable acidity (TA), ammonium (NH +) excretion. The results showed that urine TA and NH + in patients with chronic renal failure and renal tubular acidosis were significantly lower than those in the normal control group (P <0.01), but the degree of TA reduction in the former was not significantly higher than that in the latter, while there was no significant difference between the NH + . The correlation also showed that patients with chronic renal failure urine NH + and blood Cr was significantly negatively correlated. The authors discuss the characteristics and causes of renal tubular acidosis dysfunction in patients with chronic renal failure.