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为防止大鼠尾部悬吊期间，睾丸滑入腹腔造成隐睾症，建立了无隐睾雄性尾部悬吊大鼠模型。结果表明：采用腹股沟管环缩术，可有效地防止睾丸滑入腹腔，且不影响睾丸的形态与功能。尾部悬吊４周大鼠睾丸重量（对照组：１．７０±０．１９ｇ，悬吊组：０．６０±０．１６ｇ）与血清睾酮含量（对照组：９９．５±３２．７ｎｇ／ｄｌ，悬吊组：２３．０±１３．２ｎｇ／ｄｌ）明显降低（Ｐ＜０．０１），无隐睾悬吊组（ＳＴ）的睾丸重量（１．２１±０．３０ｇ）与血清睾酮水平（４０．７±３２．６ｎｇ／ｄｌ）亦下降，但其均值介于对照组与悬吊组之间。光镜观察发现悬吊组睾丸组织的曲精细管均明显萎缩，精原细胞退化与坏死，数量明显减少，曲精细管内精子数量减少。但ＳＴ组萎缩的程度较轻，且未见精原细胞坏死现象。悬吊组与ＳＴ组大鼠心肌等长收缩的静息张力无改变，发展张力均明显降低，血清睾酮水平与心肌发展张力间无相关关系。提示：无隐睾组大鼠睾丸萎缩可能是由于睾丸供血不足或垂体调节激素改变引起
To prevent rat tail suspension during the testis slide into the abdominal cavity causing cryptorchidism, the establishment of a rat model of cryptorchidism without male tail suspension. The results show that: the inguinal canal shunt surgery, can effectively prevent the testicular slide into the abdominal cavity, and does not affect the testicular morphology and function. The testicular weight (control group: 1.70 ± 0.19 g, suspension group: 0.60 ± 0.16 g) and the serum testosterone content (tail vein group: 99.5 ± 32.7 ng / dl , The suspension group: 23.0 ± 13.2ng / dl) (P <0.01), and the testicular weight (1.21 ± 0.30g) in the absence of cryptorchidism group was significantly correlated with the level of serum testosterone (40.7 ± 32.6ng / dl) also decreased, but the mean between the control group and the suspension group. Light microscopic examination showed that the testicular tissue of the suspension group were significantly atrophy of the seminiferous tubules, spermatogonial cell degeneration and necrosis, the number was significantly reduced, the amount of spermatozoa in the seminiferous tubules decreased. However, the degree of atrophy in ST group was mild, and there was no necrosis of spermatogonia. There was no change in the resting tension of isometric contractions in the suspension group and the ST group, and the developmental tension was significantly decreased. There was no correlation between serum testosterone level and myocardial development tension. Tip: no cryptorchid testis in rats may be due to testicular atrophy testis hypopituitarism or pituitary hormonal changes caused