影响输液剂热原含量因素的探讨

• 作 者: 陈明捷 苏景福 叶凤山
• 机 构: 中国人民解放军第230医院,中国人民解放军第230医院,中国人民解放军第230医院,
• 出 处: 药学情报通讯
• 发表日期: 1986年03期
• 关键词: 输液剂 热原 配制过程 热原反应 常用制剂 空调技术 预防为主 检出 室温 现代医学

输液剂在现代医学中是抢救病人和战备不可缺少的常用制剂。现在多数医院都是自制输液剂,由于条件不同,在配制过程中容易带入热原,使临床应用时出现热原反应,给患者带来痛苦。近年来由于净化和空调技术在医药方面的应用,输液剂中的热原反应有了一定程度的控制。但输液剂带入热原的因素复杂,而且在配制过程中不易检出。本文以预防为主的精神,从葡萄糖输液剂的配制到灭菌前的室温、时间限度和输液剂pH

Infusion agents in modern medicine is an indispensable and commonly used preparation to rescue patients and combat readiness. Nowadays, most hospitals are self-made infusionrs. Due to different conditions, they are easy to bring into the pyrogen during the preparation process, which causes pyrogen reaction in clinical application and brings pain to the patients. In recent years due to purification and air-conditioning technology in medicine, the pyrogen reaction in the infusion agent has a certain degree of control. However, infusion of agents into the pyrogen complex factors, but also difficult to detect in the preparation process. In this paper, the spirit of prevention, from the preparation of glucose infusion to sterilization before room temperature, time limit and infusion pH