论文部分内容阅读
目的探讨单硝酸异山梨酯治疗冠状动脉粥样硬化性心脏病(CHD)无症状心肌缺血患者的临床效果。方法选取2014年12月至2016年4月于辽宁省沈阳市苏家屯区中心医院就诊的98例CHD无症状心肌缺血患者作为研究对象,按随机数字表法将其分为对照组与观察组,各49例。对照组患者采用丹参注射液进行治疗,观察组患者采用单硝酸异山梨酯进行治疗,比较两组患者经不同方法治疗后的治疗效果以及ST段压低次数、ST段压低持续总时间。结果观察组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患者ST段压低次数与对照组患者相比明显更低,差异有统计学意义(P<0.05);两组患者ST段压低持续总时间差异无统计学意义(P>0.05)。结论单硝酸异山梨酯治疗CHD无症状心肌缺血患者具有一定治疗效果,可有效改善患者心肌缺血症状,降低心肌耗氧量。
Objective To investigate the clinical effect of isosorbide mononitrate on asymptomatic myocardial ischemia in patients with coronary atherosclerotic heart disease (CHD). Methods A total of 98 CHD patients with asymptomatic myocardial ischemia treated in Central Hospital of Sujiatun District, Shenyang City, Liaoning Province from December 2014 to April 2016 were selected as the research object. According to the random number table, they were divided into control group and observation group Group, each 49 cases. Patients in the control group were treated with Salvia miltiorrhiza injection. The patients in the observation group were treated with isosorbide mononitrate. The therapeutic effect and the number of ST depression and the duration of ST depression were compared between the two groups. Results The total effective rate of observation group was significantly higher than that of control group, the difference was statistically significant (P <0.05). The number of ST segment depression in observation group was significantly lower than that of control group (P <0.05). There was no significant difference in the total duration of ST segment depression between the two groups (P> 0.05). Conclusion Isosorbide Mononitrate can treat CHD patients with asymptomatic myocardial ischemia, which can effectively improve the symptoms of myocardial ischemia and reduce myocardial oxygen consumption.