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目的评价2010~2014年新余市疑似预防接种异常反应(Adverse Events Following Immunization,AEFI)监测工作质量,分析其发生特征。方法通过AEFI监测信息系统收集2010~2014年新余市报告的AEFI个案数据,用AEFI的监测指标进行工作质量评价,采用描述性流行病学方法对其发生特征进行分析。结果 2010~2014年新余市报告接种21种疫苗共2 162 948剂,AEFI监测病例195例(男女性别比为1.71∶1),其中一般反应125例,异常反应68例,偶合症2例,无疫苗质量事故、接种事故,无心因性反应发生;报告发生率9.02/10万剂。自2013年后,AEFI明显增加,具有明显的季节性,以7、9月份最高。AEFI监测病例48 h内报告率逐年提高至100%,48 h内调查率、3 d内调查表报告率历年均达100%。结论新余市疫苗安全性和疫苗接种服务质量较高,AEFI监测系统及时性、敏感性高。AEFI监测网络更加完善,监测工作已进入正轨。
Objective To evaluate the quality of monitoring work of suspected adverse immunization (AEFI) in Xinyu City from 2010 to 2014 and analyze the characteristics of the surveillance. Methods The data of AEFI cases reported in Xinyu City from 2010 to 2014 were collected through the AEFI monitoring information system. The quality of the work was evaluated with AEFI monitoring indicators, and the characteristics of the cases were analyzed by descriptive epidemiology. Results A total of 2,162,948 doses of 21 vaccines were reported in Xinyu City from 2010 to 2014, 195 cases were AEFI-detected (male to female ratio was 1.71: 1). There were 125 cases of general reaction, 68 cases of abnormal reaction, 2 cases of couple disease, Vaccine quality accidents, vaccination accidents, no psychological reactions occurred; the report rate of 9.02 / 10 million doses. Since 2013, AEFI has significantly increased, with a clear seasonal, the highest in July and September. The reporting rate of AEFI surveillance cases increased from year to year to 100% within 48 hours. The investigation rate within 48 hours and the survey report within 3 days reached 100% annual average. Conclusion The vaccine safety and vaccination services in Xinyu City are high, and the AEFI monitoring system has high timeliness and sensitivity. The AEFI monitoring network is more complete and monitoring is on track.