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目的探讨米力农治疗先天性心脏病合并心力衰竭患儿的临床疗效。方法选取2015年1—12月东莞康华医院收治的86例先天性心脏病合并心力衰竭患儿作为研究对象,按照就诊序号(单号、双号)将其分为研究组和对照组,各43例。对照组患儿给予常规治疗,研究组患儿在对照组基础上采用米力农进行治疗,比较两组患儿临床疗效、不良反应发生情况、治疗前后左心室射血分数(LVEF)及心率变化情况。结果研究组患儿治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);治疗后,研究组患儿的LVEF明显高于对照组,心率明显低于对照组,差异均有统计学意义(均P<0.05);两组患儿的不良反应发生率差异无统计学意义(P>0.05)。结论对先天性心脏病合并心力衰竭患儿在常规治疗基础上加用米力农临床疗效明显,可有效改善患儿心功能,且安全性较高。
Objective To investigate the clinical efficacy of Milrinone in the treatment of children with congenital heart disease complicated with heart failure. Methods Totally 86 children with congenital heart disease complicated with heart failure admitted to Dongguan Kang Wah Hospital from January to December in 2015 were selected as study subjects, and were divided into study group and control group according to their visiting numbers (single number and double number) 43 cases. Children in the control group were given routine treatment. The children in the study group were treated with Milrinone on the basis of the control group. The clinical efficacy, incidence of adverse reactions, changes in left ventricular ejection fraction (LVEF) and heart rate before and after treatment were compared between the two groups Happening. Results The total effective rate of treatment group was significantly higher than that of control group (P <0.05). After treatment, the LVEF of study group was significantly higher than that of control group, and the heart rate was significantly lower than that of control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion The clinical efficacy of Milrinone in children with congenital heart disease complicated with heart failure treated with conventional treatment is obvious, which can effectively improve the cardiac function of children with high safety.