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目的观察依达拉奉联合阿托伐他汀治疗急性脑梗死的临床疗效。方法将72例急性脑梗死患者随机分为治疗组和对照组各36例。对照组除常规治疗外给予依达拉奉治疗,治疗组在对照组基础上加用阿托伐他汀。治疗14d后观察两组患者的神经功能缺损程度及不良反应,并评定临床效果。结果治疗14d后,治疗组神经功能缺损评分(NDS)低于对照组,差异具有统计学意义(P<0.05)。治疗组总有效率为90.63%,对照组为68.75%,治疗组的总有效率明显高于对照组(P<0.05)。两组不良反应差异不显著(P>0.05)。结论依达拉奉联合阿托伐他汀治疗急性脑梗死疗效显著,安全性好,能有效促进患者神经功能恢复。
Objective To observe the clinical efficacy of edaravone combined with atorvastatin in the treatment of acute cerebral infarction. Methods 72 patients with acute cerebral infarction were randomly divided into treatment group and control group of 36 cases. The control group was treated with edaravone, except for routine treatment. The treatment group was given atorvastatin on the basis of the control group. After 14 days of treatment, the degree of neurological deficits and adverse reactions in both groups were observed and the clinical effects were evaluated. Results After 14 days of treatment, the neurological deficit score (NDS) in the treatment group was lower than that in the control group, with statistical significance (P <0.05). The total effective rate was 90.63% in the treatment group and 68.75% in the control group, and the total effective rate in the treatment group was significantly higher than that in the control group (P <0.05). Adverse reactions between the two groups showed no significant difference (P> 0.05). Conclusion Edaravone combined with atorvastatin has significant curative effect on acute cerebral infarction and good safety. It can effectively promote the recovery of neurological function in patients.