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目的:观察三维适形调强放疗对食管癌根治术后颈胸淋巴结转移者的效果。方法:通过电话随访及电子病历回顾性分析54例食管鳞癌根治术后颈胸内淋巴结转移患者调强放疗的预后。用SPSS 17统计软件分析影响预后的相关因素。结果:全组1、2、3年生存率为69%、55%、47%,中位生存时间29个月。胸部淋巴结转移患者中,淋巴结<2 cm者生存率优于≥2 cm者(χ2=6.276,P=0.012),淋巴结转移的时间为生存率影响因素。结论:三维适形调强放疗治疗食管癌根治术后颈胸淋巴结转移疗效好,淋巴结转移时间是生存率影响因素,转移淋巴结大小是胸部转移患者生存率影响因素。
Objective: To observe the effect of three-dimensional conformal IMRT on patients with cervical-thoracic lymph node metastasis after radical resection of esophageal cancer. Methods: The prognosis of 54 patients with esophageal squamous cell carcinoma after radical mastectomy and radiotherapy were retrospectively analyzed by telephone follow-up and electronic medical records. SPSS 17 statistical software analysis of prognostic factors. Results: The overall 1, 2, 3-year survival rates were 69%, 55%, 47%, and the median survival time was 29 months. The survival rate of patients with lymph node metastasis less than 2 cm was better than ≥ 2 cm (χ2 = 6.276, P = 0.012). The time of lymph node metastasis was the influencing factor of survival rate. CONCLUSION: Three-dimensional conformal IMRT is effective in treating cervical and thymus lymph node metastasis after radical resection of esophageal cancer. The lymph node metastasis time is the influencing factor of survival rate. The metastatic lymph node size is the influencing factor of survival rate in patients with thoracic metastasis.