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China has established a two-level normative struc-ture AIDS notification system with the AIDS Prevention and Control Regulations as the core and local regulations as the supplement. The problem is that the local legislations have different provisions with re-gard to the subject of notification and whether to adopt mandatory no-tification, which confronts the implementation of the AIDS notification system and the prevention of AIDS transmission with real difficulties. The different attitudes of local legislations to the mandatory notifica-tion system for AIDS essentially reflects the dilemma of legislators in balancing the right to privacy of HIV-infected patients and the right to health of their sexual partners. From the perspective of rights lim-itations, this paper aims to conducts interest balance analysis in the aspects of social urgency, public interest, substantive damage and the right to know of others and holds the view that when these two rights conflict with each other, priority should be given to the right to health of HIV-infected patients and their sexual partner as well as public health. In terms of specific systems, the AIDS Prevention and Control Regulations should establish a mandatory notification system and local legislation should take into consideration of local conditions to make specific provisions on issues of notification subject, notification procedures and confidentiality obligations after notification.