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目的:探讨睾丸胚胎癌临床、病理特点和诊疗方法。方法:回顾2005年~2015年我院收治的6例睾丸胚胎癌的临床资料,参考国内外胚胎癌病例报告并总结诊疗特点。结果:6例术后病理诊断均为胚胎癌,其中5例行睾丸根治性切除术后辅助化疗,1例行睾丸根治性切除术后辅助腹膜后淋巴结清扫及化疗等综合治疗,术后平均随访51(6~101)个月,未见复发及转移。结论:睾丸胚胎癌是一种较少见的男性恶性睾丸肿瘤,多数临床症状不明显,因睾丸肿块就诊,B超为首选检查,血清肿瘤标志物对诊断很重要。最终确诊需要依靠病理诊断,手术治疗是首选治疗方法,腹膜后淋巴结肿大者,需行腹膜后淋巴结清扫术,术后辅以辅助治疗效果更佳。
Objective: To investigate the clinical, pathological features and diagnosis and treatment of testicular embryonal carcinoma. Methods: The clinical data of 6 cases of testicular embryonal carcinoma treated in our hospital from 2005 to 2015 were retrospectively analyzed. The report of the cases of embryo carcinoma at home and abroad were summarized and the characteristics of diagnosis and treatment were summarized. Results: All the 6 cases were pathologically diagnosed as embryonal carcinoma. Five cases received adjuvant chemotherapy after radical resection of the testicle. One case received combined radical resection of the retroperitoneal lymph node and chemotherapy after radical resection of the testicle. The mean follow-up 51 (6 ~ 101) months, no recurrence and metastasis. Conclusion: Testicular embryonal carcinoma is a rare male malignant testicular tumor, most of the clinical symptoms are not obvious because of treatment of testicular tumors, B-ultrasound is the preferred examination, serum tumor markers is very important for the diagnosis. The final diagnosis need to rely on pathological diagnosis, surgical treatment is the preferred method of treatment, retroperitoneal lymph nodes, the need for retroperitoneal lymph node dissection, adjuvant postoperative adjuvant therapy is better.