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脑血管病脑萎缩患者外周血Ｔ淋巴细胞亚群初步分析太原市中心医院（０３０００９）王永兴，陈湘国我们观察了２３例脑血管病（ＣＶＤ）脑萎缩患者外周血（ＰＢ）Ｔ淋巴细胞亚群，现将结果报告如下。资料与方法２３例ＣＶＤ脑萎缩患者均经临床诊断及头颅ＣＴ证实。其中男２Ｏ例，女３例；平均年龄５２．４±７．６岁，最大年龄为６０岁（避免由增龄引起的生理性脑萎缩）。其中缺血性１３例，出血性９例，混合型１例；单纯脑室增大５例，脑沟增宽沟回缩小５例，脑室脑池脑沟扩大者１１例，重度弥漫性脑萎缩２例；选正常对照２０例，男１１例，女９例，平均年龄５３．１±６．８岁，均无神经系统疾病。方法：采用ＣＤ单克隆抗体间接免疫ＳＰＡ法，取恢复期患者ＰＢ，避免急性期应激反应对Ｔ淋巴细胞干扰，经抗凝，细胞分离，染色及镜检计数及计算百分率。结果和讨论ＣＶＤ脑萎缩患者和正常人ＰＢＴ淋巴细胞亚群测定情况见附表。２３例ＣＶＤ脑萎缩患者Ｔ淋巴细胞亚群测定与同龄正常组相比，可见：ＣＶＤ脑萎缩患者ＣＤ３，ＣＤ８百分率比正常组减少（Ｐ均＜０．０１），ＣＤ４百分率比正常值减少（Ｐ＜０．０５）；最新文献报道：“完整的左侧皮质的存在是维持正常免疫功能的主要条件。”ＣＶＤ脑萎缩患者
Cerebral vascular disease in patients with atrophy of T lymphocyte subsets in patients with primary analysis Taiyuan Central Hospital (030009) Wang Yongxing, Chen Xiangguo we observed 23 patients with cerebrovascular disease (CVD) of peripheral blood (PB) T lymphocyte subsets, The results reported below. Materials and Methods 23 patients with CVD brain atrophy were confirmed by clinical diagnosis and cranial CT. Including 2O cases of males and 3 females; mean age of 52.4 ± 7.6 years, the maximum age of 60 years (to avoid aging caused by physiological brain atrophy). Including ischemic in 13 cases, hemorrhage in 9 cases, mixed type in 1 case; simple ventricular enlargement in 5 cases, 5 cases of recurrent sulci dilated groove, 11 cases of ventricular expansion in cerebral pool sulci, severe diffuse brain atrophy 2 Cases; selected normal control in 20 cases, 11 males and 9 females, mean age 53.1 ± 6.8 years, no neurological disease. Methods: CD monoclonal antibody indirect immunotherapy SPA method was used to recover the recovery of patients with PB, to avoid acute stress response to T lymphocyte interference by anticoagulant, cell separation, staining and microscopic count and calculate the percentage. Results and Discussion The determination of PBT lymphocyte subsets in patients with CVD brain atrophy and in normal subjects is given in the attached table. T lymphocyte subsets in 23 patients with CVD brain atrophy were significantly lower than those in normal subjects (P <0.01), while the percentages of CD3 and CD8 in patients with CVD brain atrophy were significantly lower than those in normal subjects (P < <0.05). The latest literature reports that “the presence of intact left cortex is the main condition for maintaining normal immune function.” Patients with CVD brain atrophy