论文部分内容阅读
青霉素自1928年由英国细菌学家弗莱明首先发现之后,应用于临床至今已有六十余年的历史了。由于青霉素具有抗菌作用强、疗效显著、毒性低等优点,所以目前在临床上仍然将其作为抗感染的首选药物而久用不衰。 青霉素对多种球菌(葡萄球菌、链球菌、肺炎球菌、淋球菌)、革兰氏阳性杆菌(破伤风杆菌、气性坏疽杆菌、炭疽杆菌、白喉杆菌),以及螺旋体,放线菌等,均有强大的抑制作用。一般说来,它在低浓度时抑菌、高浓度时是杀菌,其抗菌
Penicillin has been used clinically for more than 60 years since it was first discovered by the British bacteriologist Fleming in 1928. Because penicillin has the advantages of strong antibacterial effect, significant curative effect and low toxicity, it is still used clinically as the drug of choice for anti-infection for a long time. Penicillin on a variety of cocci (Staphylococcus, Streptococcus, pneumococcus, Neisseria gonorrhoeae), Gram-positive bacteria (Clostridium tetani, gas anthrax, Bacillus anthracis, diphtheria bacilli), and spirochetes, actinomycetes, etc. Has a strong inhibitory effect. In general, it is bacteriostatic at low concentrations, bactericidal at high concentrations, and is antibacterial