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目的:探讨黄芪益肾汤辅助治疗糖尿病肾病临床效果。方法:选取2016年1月-2016年6月收治的80例糖尿病肾病患者为研究对象,采用随机数字表法将患者分为对照组和观察组各40例,对照组给予格列齐特和厄贝沙坦治疗,观察组在上述治疗的基础上加用黄芪益肾汤,比较两组患者临床疗效和不良反应。结果:观察组中显效32例、有效6例、无效2例,对照组分别为18例、14例、8例,两组比较差异有统计学意义(P<0.05);观察组尿β_2微球蛋白(β_2-MG)、尿微量白蛋白/尿肌酐(mALB/Ucr)、糖化血红蛋白(HbAlc)较对照组下降更明显(P<0.05),空腹血糖(FBG)两组无明显差异。结论:黄芪益肾汤辅助治疗糖尿病肾病能明显增强治疗效果,提高有效率,改善临床指标。
Objective: To investigate the clinical effect of Huangqi Yishen Decoction in the treatment of diabetic nephropathy. Methods: From January 2016 to June 2016, 80 patients with diabetic nephropathy admitted to our hospital were enrolled in this study. Patients were divided into control group and observation group by random number table method, 40 patients in each group were given Gliclazide and Eritrea Beisitan treatment, the observation group in addition to the above treatment with Astragalus Yishen Tang, clinical efficacy and adverse reactions in both groups were compared. Results: In the observation group, 32 cases were markedly effective, 6 cases were effective and 2 cases were ineffective. The control group were 18 cases, 14 cases and 8 cases, respectively. The difference between the two groups was statistically significant (P <0.05) The levels of β_2-MG, mALB / Ucr and HbAlc were significantly lower than those of the control group (P <0.05). There was no significant difference between the two groups in fasting blood glucose (FBG). Conclusion: Astragalus Yishen Decoction adjuvant treatment of diabetic nephropathy can significantly enhance the therapeutic effect, improve efficiency and improve clinical indicators.