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目的通过对大子宫阴式全子宫切除术与腹式全子宫切除术的比较，了解不同情况的大子宫采取何种手术方式对患者损伤最小。方法对两种术式的全子宫切除术的病例在手术时间、出血量、排气时间及住院天数进行对比，并对７例行阴式全子宫切除术失败者的原因进行分析。结果宫颈肌瘤、子宫下段肌瘤及极不规则大子宫行阴式全子宫切除术易失败。阴式全子宫切除术的术后平均最高体温低，肛门排气早，但术中出血、住院天数、手术时间与并发症与腹式全子宫切除术相似。结论大子宫经阴式全子宫切除术是一种安全可靠的方式，但对于有特殊情况的大子宫则经腹行全子宫切除术较方便、安全。
Objective To compare the large hysterectomy with hysterectomy and abdominal hysterectomy to understand the different conditions of the uterus to take what kind of surgery to minimize the damage to patients. Methods The cases of total hysterectomy in two kinds of operation were compared in operation time, blood loss, exhaust time and hospitalization days, and the causes of failure of vaginal hysterectomy in 7 patients were analyzed. Results of cervical fibroids, lower uterine fibroids and very irregular large uterine line vaginal hysterectomy easily failed. Vaginal hysterectomy postoperative average maximum hypothermia, anus early exhaust, but intraoperative bleeding, hospitalization days, operation time and complications and abdominal hysterectomy similar. Conclusion Large uterus transvaginal hysterectomy is a safe and reliable way, but for special cases of the large uterus by abdominal hysterectomy is more convenient and safe.