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在几项研究中,人们对血小板功能抑制剂阿司匹林和噻氯匹定(Ticlopidin,TIC)预防心肌梗塞和中风的作用进行试验。约22000例美国医生参加的医生健康研究表明,隔日服用阿司匹林325 mg使心肌梗塞危险下降47%。在对稳定型心绞痛病人的多次研究中,阿司匹林不能保护病人不发生心肌梗塞,而非稳定型心绞痛病人服用阿司匹林却能获益。意大利TIC研究组表明,TIC同样可使非稳定性心绞痛病人的心肌梗塞发生和心脏病死亡率下降。
In several studies, the role of platelet function inhibitors aspirin and Ticlopidin (TIC) in preventing myocardial infarction and stroke was tested. A doctor health study involving about 22,000 U.S. physicians showed that taking aspirin 325 mg every other day reduced the risk of myocardial infarction by 47%. In many studies of patients with stable angina, aspirin can not protect patients from myocardial infarction, but patients with stable angina who take aspirin can benefit. Italy TIC research group shows that TIC also can make patients with unstable angina patients with myocardial infarction and heart disease mortality decreased.