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目的:探讨Spitz痣的形态特征及病理诊断和鉴别诊断。方法:报道1例Spitz痣并运用光镜观察及免疫组化分析,结合文献资料对本病的临床表现,病理形态学特点及鉴别诊断进行探讨。结果:spitz痣由梭形细胞和上皮样细胞构成,细胞有一定异型性,无不其型核分裂象。结论:Spitz是一种具有独特临床病理特征的良性病变,熟悉该肿瘤的组织学特点对避免误诊为恶性黑色素瘤具有重要意义。
Objective: To investigate the morphological and pathological diagnosis and differential diagnosis of Spitz nevus. Methods: One case of Spitz nevus was reported and its clinical manifestations, pathomorphological features and differential diagnosis were analyzed by light microscopy and immunohistochemistry combined with literature data. Results: The spitz nevus consisted of spindle cells and epithelioid cells. The cells had a certain atypia without any type of mitosis. Conclusion: Spitz is a benign lesion with unique clinicopathological features. Being familiar with the histological features of the tumor is of great importance to avoid misdiagnosis as malignant melanoma.