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  5. Synthesis and antitumor evaluation of C3/C3 fluoroquinolone dimers (I): Tethered with a fused hetero

Synthesis and antitumor evaluation of C3/C3 fluoroquinolone dimers (I): Tethered with a fused hetero

来源 :中国化学快报（英文版） | 被引量 : 0次 | 上传用户：afengyu66
【摘 要】
：
Five C3/C3 fluoroquinolone dimers tethered with a fused heterocyclic ring of s-triazolo[2,1-b][1,3,4]thiadiazole derived from antibacterial quinolones were synt
【作 者】
：
Guo Qiang Hu Zhong Quan Zhang 
【机 构】
：
Institute of Chemistry & Biology,China Pharmaceutical University
【出 处】
：
中国化学快报（英文版）
【发表日期】
：
2004年期
【关键词】
：
Fluoroquinolone Dirtier Antitumor evaluation 
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Five C3/C3 fluoroquinolone dimers tethered with a fused heterocyclic ring of s-triazolo[2,1-b][1,3,4]thiadiazole derived from antibacterial quinolones were synthesized and characterized, and their in vitro antitumor activity against L1210, CHO cell lines was evaluated via the respective IC50 values.
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