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Tirapazamine是由SanofiWinthrop和SRIIntl公司研制的抗癌新药。该药的作用在于能增强放疗对细胞的杀伤力。通常认为,缺氧会降低癌细胞对放疗的敏感性,而缺氧细胞常见于实体瘤。现已开发出多种用以增加这些细胞对放疗的敏感性的药物。其中
Tirapazamine is an anti-cancer drug developed by SanofiWinthrop and SRIIntl. The drug’s role is to enhance the lethality of radiation on cells. It is generally believed that hypoxia reduces the sensitivity of cancer cells to radiotherapy, whereas hypoxic cells are common in solid tumors. A variety of drugs have been developed to increase the sensitivity of these cells to radiotherapy. among them