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顛茄散或莨菪散制剂的含量测定,药典上沒有規定。据了解有些生产單位应用浸漬或滲漉法將其作成酊剂,再按中国药典顛茄酊法进行測定。其操作費时(一次操作須6—7天)且不易掌握,往往由于檢驗問題不能解决,致使产品不能即时出厂,影响生产的正常进行。我們根据日本药局方东莨菪散法,作了部分修改后,应用于莨菪散或顛茄散的含量測定,均可得到滿意結果。此法簡單、迅速(一次操作只須8—10小时),曾用中国药典测莨菪叶法进行核对,結果一致。经介紹有关生产單位使用后,亦認为滿意。操作方法:称取試品30克,置250ml碘瓶中,加醚140ml密塞搖匀,加10ml氨試液,称定重量,在温室振搖2小时,再称重
Determination of the content of the belladonna loose or loose powder formulations, there is no prescription in the pharmacopoeia. It is understood that some production units use impregnation or leaching methods to make them into elixirs, and then measure them according to the Chinese Pharmacopoeia, belladonna method. The operation is time-consuming (6-7 days for one operation) and it is not easy to grasp. Often, the problem cannot be solved due to inspection problems. As a result, the product cannot be shipped out of the factory immediately, affecting the normal production. According to the Japanese Pharmacopoeia’s Fang Dongchao’s bulk method, we have made some modifications and applied it to the content determination of Lozenge or belladonna, and both have satisfactory results. This method is simple and rapid (only 8-10 hours for one operation). It has been verified by the Chinese Pharmacopoeia to test the temporal leaf method. The results are consistent. After the introduction of the relevant production units, they were also satisfied. Method of operation: Weigh the test sample 30g, set 250ml iodine bottle, add ether 140ml Miso shake, add 10ml ammonia test solution, weighed, shake in the greenhouse for 2 hours, and then weigh