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五十年代初发现肾上腺皮质激素(以下称CS)疗法对暴发性肝炎等重症肝炎治疗有效。嗣后,陆续确认其对迁延型肝内胆汁淤滞、自身免疫性肝炎,特别是对狼疮型慢性活动性肝炎的疗效。六十年代以后,有报道除自身免疫性肝炎外,又扩大应用于病毒性慢性活动性肝炎(CAH),据肝功化验和肝活检病理学研究结果认为有效。但是,评论CS对CAH的真正功过却是进入七十年代,即确立乙型肝炎病毒(HBV)和甲型肝炎病毒(HAV)血清学诊断技术之后。以肝炎病毒为病原的CAH,有乙型与非甲非乙型之分。在非甲非乙型肝炎病毒的
Early 50s found that adrenal cortex hormones (hereinafter referred to as CS) therapy for fulminant hepatitis and other severe hepatitis treatment effective. Subsequently, one after another to confirm their persistent intrahepatic cholestasis, autoimmune hepatitis, especially for lupus chronic active hepatitis. Since the 1960s, it has been reported that in addition to autoimmune hepatitis, but also extended to viral chronic active hepatitis (CAH), according to liver function tests and liver biopsy studies found to be effective. However, commenting on the true merits of CS toward CAH came into the seventies, after the establishment of serological diagnosis of Hepatitis B virus (HBV) and Hepatitis A virus (HAV). Hepatitis virus as the causal agent of CAH, B and non-B non-B-type points. Non-A non-B hepatitis virus