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二氯乙烷是一种卤代烃类化合物,是一种工业上广泛使用的有机溶剂,该物质产量高、毒性大、应用范围广,接触人数多,引起中毒的通常为1,2-二氯乙烷(简称DCE)[1]。国内学者陈红红通过对染毒大鼠的尿样预处理后进行气相色谱-质谱(GC-MS)分析,初步探讨硫代双乙酸二甲酯作为接触DCE的生物标志物的可行性[2]。在项目组前期研究中,通过比较暴露在DCE环境中作业的工人与明确不接触DCE的作
Dichloroethane is a halogenated hydrocarbon compound, is an industrially widely used organic solvent, the material of high yield, toxicity, wide range of applications, the number of contacts, causing poisoning is usually 1,2-bis Chloroethane (referred to as DCE) [1]. The domestic scholar Chen Honghong probed the feasibility of dimethyl thiodiacetate as a biomarker for exposure to DCE by gas chromatography-mass spectrometry (GC-MS) analysis of pretreated urine samples from exposed rats. In a previous study in the project team, by comparing workers exposed to DCE operations with those explicitly exposed to DCE