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目的研究注射用头孢噻利治疗急性细菌性呼吸道和泌尿道感染的有效性和安全性。方法用双盲随机平行对照试验方法,以头孢他啶作为对照药。头孢噻利(127例)和头孢他啶(125例)均为每日2.0~4.0g,分2次静滴,疗程为7~14天。结果治疗后,2组总有效率分别为94.49%,92.00%;细菌清除率分别为96.26%,96.23%。药物不良反应发生率分别为5.43%,3.88%。结论注射用头孢噻利治疗急性细菌性呼吸道和泌尿道感染有效、安全,优于头孢他啶。
Objective To study the efficacy and safety of ceftizuril for the treatment of acute bacterial and urinary tract infections. Methods Double-blind randomized controlled trials with ceftazidime as control. Ceftifulny (127 cases) and ceftazidime (125 cases) were daily 2.0 ~ 4.0g, intravenous infusion 2 times, the course of treatment is 7 to 14 days. Results After treatment, the total effective rates of the two groups were 94.49% and 92.00% respectively; the bacterial clearance rates were 96.26% and 96.23% respectively. Adverse drug adverse reactions were 5.43%, 3.88%. Conclusion Ceftibulum injection for acute bacterial respiratory and urinary tract infections effective and safe, superior to ceftazidime.