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苯骈二氮杂(艹卓)类药物是一类广泛应用的抗焦虑药。焦虑和恐惧在人们的日常生活中是很常见的,在遇到威胁和某种刺激而感到焦虑是一种正常现象,但当焦虑无缘无故地引起并严重到无法控制时,就成为一种病态。长期以来人们一直与这种疾病作斗争,追溯到人类的启蒙时期,人们就利用某些天然药物如大麻、阿片和乙醇来治疗焦虑,人们最早使用的合成抗焦虑药是巴比妥类,它虽然剂量小,药效大,但过量会产生危险,并有成瘾性。到了1954年,眠尔通的问世是神经药理学上的一个新的里程碑,眠尔通是由镇静和肌松药麦酚生的改造而产生的,可以认为它是第一个有效的抗焦虑药,它可以控
Benzodiazepines are a widely used class of anti-anxiety drugs. Anxiety and fear are common in people’s daily lives, and it is normal to feel anxiety in the face of threats and certain stimuli, but it becomes a pathological condition when anxiety is unreasonably caused and severely uncontrollable . People have long been fighting the disease, and dating back to the period of human enlightenment, some natural medicines such as cannabis, opium and ethanol were used to treat anxiety. The earliest synthetic anxiolytic drug was barbiturate. Although the dose is small, effective, but excessive will be dangerous and addictive. By 1954, the advent of Mellon was a new milestone in neuropharmacology. Mellon was produced by the modification of sedative and muscle-relaxating gluconeol, and it is believed to be the first effective anxiolytic Medicine, it can control