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[目的]探索颈动脉粥样斑块与冠状动脉粥样斑块的相关性。[方法]选取2008.01~2009.05入住某院心内科的患者89例作为研究对象,依据冠状动脉造影将其分为研究组及对照组。用超声检测两组患者颈动脉粥样斑块的分布情况,将造影结果与超声检测结果进行统计处理。[结果]研究组45例检出斑块,对照组中33例未检出斑块,两组病例颈动脉内中膜厚度差异有统计学意义(t=2.6959,P=0.0084);颈动脉狭窄程度与冠状动脉粥样斑块相关(χ2=50.7788,P=0.0000,Pearson列联系数=0.6027);颈动脉粥样斑块发生的部位数与冠状动脉粥样斑块发生的血管支数有关(χ2=69.5209,P=0.0000,Pearson列联系数=0.6622)。颈动脉内中膜厚度增加的程度与冠脉脉粥样斑块的相关性不确定(rs=0.6,P﹥0.05)。通过颈动脉粥样斑块的情况了解冠脉粥样斑块的情况,Sen=88.2353%,Spe=86.8421%,Acc=87.6404,YI=0.7508。[结论]颈动脉粥样斑块与冠状动脉粥样斑块是相关的,通过超声检测颈动脉粥样斑块,间接了解心肌冠状动脉粥样斑块情况是可行的,可指导冠心病患者的治疗、效果判断、随访观察。
[Objective] To explore the correlation between carotid atherosclerotic plaques and coronary atherosclerotic plaques. [Methods] A total of 89 patients admitted to a hospital from January 2008 to May 2009 were selected as study subjects and divided into study group and control group according to coronary angiography. Ultrasound was used to detect the distribution of carotid atherosclerotic plaques in both groups, and the results of contrast and ultrasound were statistically analyzed. [Results] There were 45 plaques detected in the study group and 33 plaques in the control group. There was significant difference in the carotid IMT between the two groups (t = 2.6959, P = 0.0084); carotid stenosis (Χ2 = 50.7788, P = 0.0000, Pearson’s coefficient of association = 0.6027). The number of carotid atherosclerotic plaque was related to the number of vessels in coronary atherosclerotic plaque χ2 = 69.5209, P = 0.0000, Pearson rank = 0.6622). The correlation between carotid intima-media thickness and coronary artery plaque was uncertain (rs = 0.6, P> 0.05). According to the situation of carotid atherosclerotic plaque, we know the situation of coronary plaque, Sen = 88.2353%, Spe = 86.8421%, Acc = 87.6404, YI = 0.7508. [Conclusion] Carotid artery atherosclerotic plaque is related to coronary atherosclerotic plaque. It is feasible to detect carotid artery atherosclerotic plaques through ultrasound and to understand the coronary atherosclerotic plaque directly. It can guide the patients with coronary heart disease Treatment, the effect of judgment, follow-up observation.