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目的观察异位妊娠输卵管切除术对卵巢储备功能的影响。方法将120例异位妊娠患者作为试验组,其中试验A组60例采用保守治疗,试验B组60例采用输卵管切除术,另选取健康女性60例作为对照组,对比各组术前、术后1个月、术后3个月抗苗勒管激素(AMH)、卵泡刺激素(FSH)、黄体生成素(LH)、孕酮(P)、雌二醇(E2)水平。结果试验A组治疗前、治疗1个月、3个月AMH、FSH、LH、P及E2水平与对照组比较差异无统计学意义(P>0.05);与对照组、试验A组同时期及试验B组术前相比,试验B组治疗1个月、3个月后AMH、E2水平显著降低,FSH显著升高,差异均有统计学意义(P<0.01)。结论异位妊娠患者输卵管切除术后卵巢储备功能降低,有生育要求的育龄妇女尽量避免输卵管切除,尽可能采取药物等保守治疗,以保护卵巢功能。
Objective To observe the effect of ectopic pregnancy tubal excision on ovarian reserve function. Methods 120 cases of ectopic pregnancy patients as the experimental group, of which 60 cases of experimental group A conservative treatment, 60 cases of test group B by tubal resection, and the other 60 healthy women as a control group, comparing each group before and after surgery 1 month, and 3 months after operation. The levels of anti-Mullerian hormone (AMH), follicle-stimulating hormone (FSH), luteinizing hormone (LH), progesterone (P) and estradiol (E2) Results There was no significant difference in AMH, FSH, LH, P and E2 levels between the two groups before treatment, one month and three months after treatment (P> 0.05) In the experimental group B, the levels of AMH and E2 were significantly decreased and the FSH were significantly increased in the experimental group B at 1 month and 3 months after the treatment. The differences were statistically significant (P <0.01). Conclusion Ovarian reserve is reduced in patients with ectopic pregnancy after oviduct resection. Women of childbearing age who have reproductive requirements should avoid tubal resection as much as possible and adopt conservative treatment such as medicine to protect ovary function.