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作者曾测定饮用6个月或3～6周含铅水的妊娠大鼠的组织及血中的铅含量,结果确定;铅容易从母鼠传递给胎鼠及新生鼠,发育中的器官对铅的生物作用比成年鼠更为敏感。雌鼠饮含铅1ppm的水150天,继之饮用正常水50天后交配,其新生鼠体内的铅负荷仍不断增加,说明器官中贮存的铅在妊娠时仍不断动员出来。根据所观察的生化指标,可以认为母鼠在妊娠前或妊娠期间,从妊娠仔鼠的无作用水平来考虑,母鼠饮用水中铅的摄入量应在1ppm左右,此时新生仔鼠的血铅含量低于3μg/100ml。
The authors have determined the lead levels in the tissues and blood of pregnant rats drinking 6 months or 3 to 6 weeks of lead-containing water, the results determined; lead easily from the mother to the fetus and newborn rats, developing organs of lead The biological effects are more sensitive than adult mice. Females drink lead 1ppm of water for 150 days, followed by drinking normal water after 50 days of mating, the newborn rats in the lead load is still increasing, indicating organ storage of lead in pregnancy is still constantly mobilized out. According to the biochemical indicators observed, it can be considered before or during pregnancy in pregnant women, from the no effect of pregnancy offspring to consider the amount of lead intake of drinking water in the mother should be about 1ppm, then newborn offspring Blood lead levels below 3μg / 100ml.