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目的:探讨软组织肉瘤补充广泛切除术的原因及患者预后的影响方法:回顾性分析2007年7月至2011年3月收治的外院误诊为良性肿瘤而行局部切除的原发软组织肉瘤患者78例。主要观察终点为肿瘤的复发转移,分析肿瘤残留情况对患者预后的影响。结果:补充广泛切除术后,中位随访时间是17.4个月,其中复发3例,转移5例,死亡3例。Kaplan-Meier法计算1年无瘤生存率为93.6%,3年无瘤生存率92.3%。初次术后肿瘤残留共40例,占52%。初次手术后肿瘤残留组和非残留组生存无差异结论:患者在非计划性切除后肿瘤残留率较高,接受补充广泛切除术是必要的。补充广泛切除原因多为术前无明确病理诊断,无影像学检查。软组织肉瘤发病率较低,在临床上应慎重处理。
Objective: To explore the reasons for extensive resection of soft tissue sarcoma and the prognosis of patients.Methods: A retrospective analysis of 78 patients with primary soft tissue sarcoma excised from benign and malignant tumors from July 2007 to March 2011 was performed. The primary endpoint was the recurrence and metastasis of the tumor, and the effect of residual tumor on the prognosis of the patients was analyzed. Results: After extensive resection, the median follow-up time was 17.4 months, of which 3 were recurrence, 5 were metastasis and 3 were death. Kaplan-Meier calculated one-year disease-free survival rate of 93.6%, 3-year disease-free survival rate of 92.3%. The first postoperative residual tumor in 40 cases, accounting for 52%. No difference in survival between residual and non-residual tumor after primary surgery Conclusion: Patients with higher residual tumor rates after unplanned resection are necessary for extensive resection. Replenishment due to extensive excision of many preoperative no clear pathological diagnosis, imaging examination. Low incidence of soft tissue sarcoma, should be carefully treated in the clinic.