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目的探讨氯吡格雷联合阿司匹林治疗急性心肌梗死的临床疗效。方法选取2014年1月—2015年1月鲁山县人民医院心内科收治的急性心肌梗死患者90例,按随机分配原则分为观察组45例和对照组45例。观察组予以氯吡格雷联合阿司匹林治疗,对照组予以氯吡格雷治疗。观察两组患者的临床疗效及生活质量评分。结果观察组总有效率高于对照组,差异有统计学意义(P<0.05)。观察组患者心理功能、躯体功能、社会功能评分均高于对照组,差异有统计学意义(P<0.05)。结论采用氯吡格雷联合阿司匹林治疗急性心肌梗死患者,临床疗效显著,且能改善患者的生活质量。
Objective To investigate the clinical efficacy of clopidogrel combined with aspirin in the treatment of acute myocardial infarction. Methods 90 acute myocardial infarction patients admitted to Lushan County People’s Hospital from January 2014 to January 2015 were randomly divided into observation group (45 cases) and control group (45 cases). The observation group was given clopidogrel combined with aspirin, and the control group was treated with clopidogrel. The clinical efficacy and quality of life scores of two groups were observed. Results The total effective rate in the observation group was higher than that in the control group, with significant difference (P <0.05). The scores of psychological function, physical function and social function in the observation group were higher than those in the control group, with significant difference (P <0.05). Conclusion Clopidogrel combined with aspirin in patients with acute myocardial infarction, clinical significant effect, and can improve the quality of life of patients.