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尽管还不清楚丙型肝炎病毒(HCV)基因是否整合到宿主染色体DNA(大概是不可能的),但在多数患者中,HCV可导致慢性感染、慢性肝炎和肝硬化,并由该病导致肝细胞癌(HCC)的流行病学证据正在增加.非甲非乙型肝炎病毒与HCC最近已开始积累血液传播的非甲非乙型肝炎病毒(NANBV)感染与HCC之间病因相关的证据.由于缺乏文献,证明这种相关性是困难的.直至最近,血液传播的NANBV特异性血清学试验和在HBV高发区进行的HCC研究的许多事实,才肤浅地了解了NANBV在肝脏疾病中的作用.两者相关性的证据来自下列观察:1.在低发区,仅较小比例的HCC有慢性HBV感染证据,不象高发区那样,大多数HCC病例HBsAg是阳性的.相反,不管地理起源,大多数HCC是由肝硬化产生的.因此,在地理基础上(而不在数字
Although it is not yet clear (probably not possible) that the hepatitis C virus (HCV) gene is integrated into host chromosomal DNA, in most patients HCV can cause chronic infections, chronic hepatitis and cirrhosis and the disease causes the liver Epidemiological Evidence for Cell Carcinoma (HCC) is Increasing Evidence that the non-A, non-B, and HCC have recently started to accumulate blood-borne non-A, non-B hepatitis B virus (NANBV) The lack of literature proving that this correlation is difficult has led to a superficial understanding of the role of NANBV in liver disease until recently, many of the facts of the NANBV-specific serological tests of blood transmission and HCC studies in areas of high HBV prevalence. Evidence for the association between the two is based on the following observations: 1. In low-risk areas, only a small proportion of HCC has evidence of chronic HBV infection, and most HCC cases are not positive for HBsAg, as in high-risk areas.On the contrary, regardless of geographical origin, Most HCCs are caused by cirrhosis and therefore, on a geographical basis (not in numbers