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目的观察阿奇霉素序贯治疗与红霉素静脉滴注+阿奇霉素口服序贯治疗儿童支原体肺炎的临床疗效及成本。方法支原体肺炎患儿90例随机分为观察组和对照组各45例。观察组予以阿奇霉素序贯治疗,对照组给予红霉素静脉滴注+阿奇霉素口服序贯治疗。观察2组临床疗效、临床症状和体征恢复时间、住院时间、治疗费用及不良反应情况。结果 2组总有效率差异无统计学意义(P>0.05);治疗组退热时间长于对照组,住院时间短于对照组,治疗费用低于对照组,不良反应发生率低于对照组,差异均有统计学意义(P<0.05或P<0.01)。结论阿奇霉素序贯疗法治疗儿童支原体肺炎是一种经济、有效的方法,值得临床推广应用。
Objective To observe the clinical efficacy and cost of sequential treatment of azithromycin and erythromycin intravenous infusion plus azithromycin oral sequential treatment of children with mycoplasma pneumonia. Methods 90 cases of children with mycoplasma pneumonia were randomly divided into observation group and control group of 45 cases. The observation group was given azithromycin sequential treatment, the control group was given erythromycin intravenous infusion + azithromycin oral sequential treatment. The clinical efficacy, clinical symptoms and signs recovery time, hospital stay, treatment costs and adverse reactions were observed. Results There was no significant difference in the total effective rate between the two groups (P> 0.05). The antipyretic time in the treatment group was longer than that in the control group, the length of hospitalization was shorter than that in the control group, the treatment cost was lower than that in the control group, and the incidence of adverse reactions was lower than that in the control group All were statistically significant (P <0.05 or P <0.01). Conclusion Sequential azithromycin treatment of children with mycoplasma pneumonia is an economical and effective method, worthy of clinical application.