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目的探讨美蓝染色法前哨淋巴结测图技术在非小细胞肺癌手术中应用的可行性和对术后病理分期的影响。方法选取60例手术治疗的非小细胞肺癌患者,术中在肿瘤周围注射美蓝并寻找前哨淋巴结,检验前哨淋巴结检出率,并对常规病理检查阴性的前哨淋巴结行连续切片及免疫组化检测微转移。结果60例患者中共有55例(92%)检测到前哨淋巴结,其中22例患者前哨淋巴结及其他淋巴结未发现转移,有4例前哨淋巴结发现有微转移存在。结论美蓝染色法前哨淋巴结测图技术在非小细胞肺癌手术中的应用是可行的,此技术可以提高术后病理分期的准确性。
Objective To investigate the feasibility of using methylene blue staining for sentinel lymph node mapping in non-small cell lung cancer surgery and its effect on postoperative pathological staging. Methods Sixty surgically treated patients with non-small cell lung cancer were selected. Methylene blue was injected into the tumor around the tumor and looked for sentinel lymph node. The detection rate of sentinel lymph node was examined. Sequencing and immunohistochemistry were performed on the sentinel lymph node, which was negative for routine pathological examination. Micro-transfer. Results Sentinel lymph nodes were detected in 55 (92%) of the 60 patients. Among them, no metastasis was found in the sentinel lymph nodes and other lymph nodes in 22 patients, and micrometastases were found in 4 sentinel lymph nodes. Conclusion Methylene blue staining of sentinel lymph node mapping in non-small cell lung cancer surgery is feasible, this technique can improve the accuracy of postoperative pathological staging.