论文部分内容阅读
海轮碱Ⅱ是一个较为理想的新的肌松剂。在前文基础上,本文用整体放射自显影技术对本品在怀孕大鼠体内的分布进行了研究。 1.方法 [~3H]海轮碱Ⅱ系中科院上海原子核所制备,放射性比活度为6Ci/mmol,放化纯度>90％。该药是2％乙醇水溶液,以生理盐水稀释后供静脉注射。取妊娠十八天的大鼠3只,尾静脉注射[~3H]海轮碱Ⅱ1mCi/kg(137μg/kg),分别于给药后2分、4小时及24小时将动物投入己烷-干冰(-78℃)溶液中速冻处死,
Hydrochloride Ⅱ is a more ideal new muscle relaxant. On the basis of the previous article, this article with the whole autoradiography of the goods in pregnant rats in vivo distribution were studied. 1. Method [~ 3H] HYDROTHERMAL Ⅱ is prepared by the nucleus of Shanghai Institute of Science and Technology of China with a radioactivity of 6Ci / mmol and a radiochemical purity of> 90%. The drug is 2% ethanol solution diluted with saline for intravenous injection. Three rats of eighteen days of gestation were injected intravenously with [~ 3H] sodium pyrithione Ⅱ1mCi / kg (137μg / kg) at the tail vein. The animals were dosed with hexane-dry ice at 2, 4 and 24 hours after dosing -78 ℃) solution was killed by freezing,