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为了进一步验证肾综合征出血热（ＨＦＲＳ）病毒在人体内存在垂直传播的途径，采用间接免疫荧光法和病毒分离技术对一位临产前患ＨＦＲＳ的孕妇及其早产儿进行了ＨＦＲＳ病毒垂直传播的探讨。结果从早产儿脐带血中分离出一株ＨＦＲＳ病毒，并且从孕妇血、早产儿脐带血和早产儿血中都测到ＩｇＭ和ＩｇＧ抗体。由于血标本的采集是在无菌条件下进行，可排除其他传播途径，从而认为早产儿感染ＨＦＲＳ病毒是通过母婴垂直传播的。
In order to further verify the existence of vertical transmission of HFRS virus in humans, indirect immunofluorescence and virus isolation techniques were used to detect the vertical transmission of HFRS virus in pregnant women and their premature infants with prenatal HFRS Discussion. Results A HFRS virus was isolated from the umbilical cord blood of premature infants and IgM and IgG antibodies were measured from maternal blood, cord blood from premature infants and blood from premature infants. Since the collection of blood samples is performed under sterile conditions, other routes of transmission can be ruled out, so that premature children infected with HFRS virus is transmitted vertically through mother and baby.