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目的 调查铜陵地区特定人群GBV C/G型病毒性肝炎 (简称庚型肝炎 )病毒 (HGV)感染状况 ,加强特定人群HGV的检测 ,以阻断庚型肝炎的流行。方法 聚合酶链反应检测血清HGVRNA。结果 自愿献血员HGVRNA阳性率 1 77% (4 / 2 2 6 ) ,职业献血员HGVRNA阳性率 6 42 %(2 8/ 436 ) ,职业献血员HGVRNA阳性率明显高于自愿献血员 (P <0 0 1)。甲型肝炎、慢乙肝、慢丙肝、非甲～戊型肝炎及血透患者HGVRNA阳性率分别为 1 5 6 % (1/ 6 4)、11 11% (6 / 5 4)、19 5 7% (9/ 46 )、8 33 % (3/ 36 )及 16 6 7%(8/ 48)。结论 铜陵地区特定人群中均存在不同程度的HGV感染 ;因此 ,在大力提倡全民义务献血的前提下 ,应加强献血员 ,尤其职业献血员以及血透、输血等患者的HGV筛查 ,以阻断庚型肝炎的流行。
Objective To investigate the infection status of GBV C / G virus (HGV) in specific population in Tongling area, and to strengthen the detection of HGV in specific population so as to block the prevalence of hepatitis G virus. Methods Serum HGVRNA was detected by polymerase chain reaction. Results The positive rate of HGVRNA in voluntary blood donors was 1 77% (4/226), that of professional blood donors was 62 42% (28/436), and that of professional blood donors was significantly higher than that of voluntary blood donors (P 0 0 1). The positive rates of HGVRNA in hepatitis A, chronic hepatitis B, chronic hepatitis C, non-hepatitis E and hemodialysis patients were 165% (1/16), 1111% (6/54), 195.7% (9/46), 8 33% (3/36) and 16 6 7% (8/48) respectively. Conclusion There are different degrees of HGV infection in specific population in Tongling area. Therefore, HGV screening of blood donors, especially professional blood donors, hemodialysis patients and blood transfusion patients should be strengthened under the precondition of promoting voluntary blood donation. Hepatitis G epidemic.