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用荧光分光光度法测走利血平片溶出度,荧光强度稳定,线性关系良好(r=0.9996),平均回收率96.77％,变异系数1.96％。经考查表明不同处方和工艺所生产的片剂,其溶出度不同。建议将60min内利血平片的溶出量不少于标示量的75％作为控制标准。
Fluorescence spectrophotometry was used to determine the dissolution of reserpine tablets. The fluorescence intensity was stable and the linearity was good (r = 0.9996). The average recovery was 96.77% and the coefficient of variation was 1.96%. After examination showed that different prescriptions and processes produced tablets, the dissolution of different. It is recommended that the amount of dissolution of 60min Neprilysin tablets not less than 75% of the labeled amount as a control standard.