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肺炎球菌仍是儿童细菌性感染的一种主要病原体。作者于1979年1月～1984年12月在美国亚拉巴马儿童医院对肺炎球菌感染患儿进行了临床和流行病学调查。5年内共分离到肺炎球菌1,310株,其中44份为脑膜炎患儿,172例为菌血症,787例为中耳炎,307例为呼吸道疾病和其他感染患者。调查结果表明,在脑膜炎病例中,肺炎球菌6型最为常见,约占病例的1/3;其次为14、18、3、19和23型;菌血症中,最常见的五型为6、14、18、19和23型,共占病例总数的74%,其中14型最多见,占30％,而3型只占1.7％;19型是中耳炎的主要致病菌型,约占病例的28%,其次是6型,占14.8%,14型占14.0%,23型占11.2%,3型占8.3%;
Pneumococci are still a major causative agent of bacterial infections in children. The authors conducted a clinical and epidemiological investigation of children with pneumococcal infection at the Children’s Hospital in Alabama, January 1979-December 1984. A total of 1,310 pneumococcal isolates were isolated within 5 years, of which 44 were meningitis, 172 were bacteremia, 787 were otitis media, and 307 were respiratory and other infections. In the meningitis cases, pneumococcal type 6 was the most common, accounting for about one-third of cases; followed by types 14, 18, 3, 19 and 23; and the most common type of bacteremia was type 6 , 14, 18, 19 and 23, accounting for 74% of the total number of cases, of which 14 are the most common, accounting for 30%, while the type 3 only 1.7%; 19 is the main pathogenic otitis media, accounting for about cases 28%, followed by type 6, accounting for 14.8%, type 14 accounting for 14.0%, type 23 accounting for 11.2% and type 3 accounting for 8.3%.