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患者47岁,男性,因瘤型麻风入院。过去无肝病史。发育中等,肝在肋下2cm,质软,无触痛;脾未触及。疗前麝浊4u,谷丙转氨酶23u,锌浊7u,尿常规检验无异常。入院后第四天开始用联合化疗(利福平600mg/每月一次,氨苯砜100mg/日,丙硫异烟胺400mg/日)。服药45天后食欲下降,恶心、乏力;肝大如前、质中等,巩膜明显黄染,停服利福平和丙硫异烟胺,以50%葡萄糖加Vit C和Vit B3静脉注射,3天后出现便血,少尿,腹胀,黄疸加剧。肝脾触诊不清楚,
47-year-old male, admitted to hospital for leprosy. No history of liver disease in the past. Medium development, liver in the ribs 2cm, soft, no tenderness; spleen not touched. Before treatment musk turbidity 4u, alanine aminotransferase 23u, zinc turbidity 7u, urine tests were normal. On the fourth day after admission, the combination chemotherapy (rifampicin 600 mg / once monthly, dapsone 100 mg / day and prothiostamide 400 mg / day) was started on the fourth day after admission. 45 days after taking the drug appetite decreased, nausea, fatigue; liver as before, medium quality, scleral obvious yellow dye, stop taking rifampicin and prothiocarbamide, 50% glucose plus Vit C and Vit B3 intravenous injection, 3 days after the emergence of Blood in the stool, oliguria, bloating, increased jaundice. Liver and spleen palpation is not clear,