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乳腺癌的发生受个体因素与环境因素的共同作用。本研究观察了乳腺癌患者癌组织附近正常乳腺组织中的芳香族ＤＮＡ加合物与个体细胞色素Ｐ450 (ＣＹＰ) 1Ａ1、Ｎ 乙酰基转移酶 2 (ＮＡＴ2 )、谷胱甘肽转移酶 (ＧＳＴ)Ｍ1基因多态性的关系 ,从而探讨乳腺癌发生过程中的基因 环境?
The occurrence of breast cancer by the combination of individual factors and environmental factors. This study investigated the effects of aromatic DNA adducts and individual cytochrome P450 (CYP) 1A1, N-acetyltransferase 2 (NAT2), glutathione transferase (GST) M1 gene polymorphism in order to explore the genetic environment in the process of breast cancer?